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Gross and Fine Motor Development in 45,X and 47,XXX Girls | Articles | Pediatrics

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Neuromuscular deficits have been described in 47,XXY and 47,XYY boys, grand cayman island escort gross and fine motor development of girls with sex chromosome aneuploidy has not been extensively studied. Twenty-one propositae, 8 to 19 years of age, identified through newborn screening to be 45,X, 47,XXX, or 45,X mosaic, and 11 control girls were evaluated by a physical therapist unaware of their genetic constitution.

The clinical assessment confirmed the BOTMP findings, with 13 propositae xxx dysfunctional sensory-motor integration.

45,X/47,XXX Mosaicism and Short Stature

A delay in the age of independent walking confirmed the consistency of motor developmental dysfunction throughout time. Sex chromosome mosaics were more similar xxx control girls. The gross and fine motor delays were frequently associated with a moderate to xxx language dysfunction which adversely affected classroom performance. Regular developmental assessments of children with sex chromosome aneuploidy, including sensory-motor integration, should assist in the identification of early developmental delays and permit appropriate intervention.

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